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Vitamin E - Has been shown to be helpful for the breast problems, mood swings, irritability. Magnesium is classified as ‘nature's tranquilliser', It is vital in treating those aspects of the PMS that relate to anxiety. When taken with Vitamin B6 it become more effective. GLA Omega 6 essential fatty acids (linoleic acid) are converted to gamma linolenic acid (GLA) that is found in plants such as evening primrose, borage and starflower. Spironolactone, a medication that blocks hormone responsible for bloating, swelling, can relieve PMS responses. In certain cases, birth control therapy in for of oral contraceptives is used to suppress and regulate ovulation and lessen PMS responses overall. Since synthetic progesterone used in certain birth control pills has actually been shown to cause PMS, great care and experience are necessary in managing this therapy.

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Other management involves antidepressants such as Prozac, Paxil, Sarafem, Zoloft, which raise levels of serotonin. These medications have proven to be effective in PMS symptoms because they block the break down of serotonin in the brain, increase amount of serotonin will have to live with. There will always be good, better, best days, but by taking control of PMS, learning how to live life out from under the black cloud of PMS, it is possible to learn hoe to feel better all month long.